"Although the world is full of suffering, it is also full of the overcoming of it."
– Hellen Keller
A cure for
rhabdomyosarcoma
Support and research toward finding a cure for this deadly form of
cancer that affects children and young adults.
Help with what you can. Any amount helps the foundation.
Projects supported by the foundation
Genetic research
The research team led by Professor Christopher Vakoc at Cold Spring Harbor Laboratory has made important progress in its goal of developing targeted therapies for rhabdomyosarcoma.
In a project led by PhD student Martyna Sroka, a key discovery has been made that can allow for the ‘conversion’ of rhabdomyosarcoma tumor cells into normal muscle.
Novel therapies
A project led by MD/PhD student Cristian Lopez-Cleary is honing-in on a compelling new vulnerability in sarcoma, called MyoD. He is trying to develop novel therapies that can exploit MyoD as an Achilles heel of this tumor.
Epigenetics and genome editing
Finally, a project led by Toyoki Yoshimoto, MD/PhD, a board certified sarcoma pathologist from Japan, is discovering novel drug cocktails with improved activity over existing chemotherapies.
His approach takes advantage of advances in the field of EPIGENETICS and in GENOME EDITING, which includes technology for effective gene control using chemical-genetic perturbations.
Michelle's clubhouse
Help provide patient families with funds to cover the cost of hotels, gas, parking, meals, childcare, and other incidentals associated with a child’s treatment.
News
What’s happening right now in Michelle Paternoster Foundation.
Stopping a rare childhood cancer in its tracks
Scientists at Cold Spring Harbor Laboratory (CSHL) have discovered a new drug target for Ewing sarcoma, a rare kind of cancer usually diagnosed in children and …
Once rhabdomyosarcoma, now muscle
“Every successful medicine has its origin story. And research like this is the soil from which new drugs are born,” says Cold Spring Harbor Laboratory …
CSHL scientists and families who help fund them share goals, optimism
By Daniel Dunaief A group of people may prove to be the guardian angels for the children of couples who haven’t even met yet. After …